Announcement

Collapse

Welcome to the updated and refreshed Tourette Canada Online Forum!

Tourette Canada Online Forum is a free, safe, moderated online community where registered users can exchange ideas, information and support about issues related to Tourette Syndrome. Tourette Canada has recently changed the server and refreshed the pages so returning members will notice a brighter look. Tourette Canada welcomes back two former moderators, Janet Rumsey and Cathy Wylie, to the Forum. Their knowledge and insight will serve the Tourette Forum participants with dedication and expertise.

We would like to thank the administrators and moderators who have dedicated countless hours to build and maintain the Forum. We look forward to continuing to provide a place for individuals and families affected by Tourette Syndrome and its associated disorders to get information, exchange information with others, and connect with the affiliates and support available across Canada.
See more
See less

Anyone noticed weight gain with Orap?

Collapse
X
  • Filter
  • Time
  • Show
Clear All
new posts

  • Anyone noticed weight gain with Orap?


    Hello to all. I am new to this forum. I was diagnosed with TS 9 years ago and have been on orap (pimozide) for 7 of those years. Also, I have been on apro-sertraline for the past 2 1/2 years to deal with minor OCD.
    The reason I am writing is to see if there are any other teens out there who have noticed weight gain and appetite gain due to one or both of these medications. I tried to gradually discontinue taking the sertraline (from 75 mg) but was unsuccessful and am now back on 50 mg. I also tried reducing the orap but found that my tics were becoming worse immediately.
    I was wondering if anyone had any tips for me?
    Thanks,
    teenwithtics

  • #2
    Anyone noticed weight gain with Orap?

    i have no tips for you,, but ever since i started with orap i have gained alot of weight, my doctor says that orap does that, but like you, everytime i ut it off, my tick ome back

    Comment


    • #3
      Anyone noticed weight gain with Orap?

      Hi Teenwithtics!

      Welcome to the TS Forum and thanks for posting an interesting question. Based on the product monograph of Orap (pimozide) the side effect of weight gain is unclear. In fact the product monograph of sertraline (Zoloft) reports a small percentage of patients report weight loss.

      This is not to say your weight gain is not related to your medication, and you should discuss your concern with your physician.

      The manufacturer of Orap does warn about drinking grapefruit juice or eating grapefruit while taking Orap. This is a problem with several medications as grapefruit tends to increase the concentration of the medication in your system.

      You may want to discuss your medications with a specialist and make sure the specialist is told that you are taking sertraline along with pimozide and the dosages of each, along with any other meds you may be taking.

      This would be the wise and prudent course to follow concerning your legitimate concerns about weight changes and your medications.

      Are you being treated by a specialist now or by your family physician?
      Steve

      Dum spiro spero....While I breathe, I hope

      Tourette Canada Homepage
      If you enjoy the TC Forum, please consider a Tourette Canada membership
      Please visit our sister Forum: Psychlinks Psychology and Mental Health Support Forum

      Comment


      • #4
        Anyone noticed weight gain with Orap?

        i am being treated currently by a specialist that i see about once or twice a year

        Comment


        • #5
          Anyone noticed weight gain with Orap?

          >>>I am being treated currently by a specialist that i see about once or twice a year<<

          Great! Have you discussed the weight gain issue with your specialist? If you have concerns about a particular problem after your doctor prescribes medication, the doctor expects you to call back and to report the problem. It's the only way you can find out if the problem is related to your meds.

          Doctors are used to getting calls from their patients with concerns about side effects, so arrange with your parents or whoever is working with you to contact the doctor.

          Waiting 6 to 12 months is too long to endure side effects from a medication, if indeed your problem is medication related.

          Please keep us informed of your progress and the outcome of your inquiry.

          Your input will be helpful to others who may be experiencing the same problem.
          Steve

          Dum spiro spero....While I breathe, I hope

          Tourette Canada Homepage
          If you enjoy the TC Forum, please consider a Tourette Canada membership
          Please visit our sister Forum: Psychlinks Psychology and Mental Health Support Forum

          Comment


          • #6
            Weight gain

            I've noticed weight gain can be an issue for a number of medications out there. This can be hard to deal with long term.

            I think the first response is natural to try to curb your dose or frequency to help but never a good one.
            I am gilty of this first hand. If telling your Doctor does not help much, then ask him for assistance to change your intake and balance out your daily habits.

            My Doctor understood but the main factor was that my medication was working and this was mostly what he was interested in. Sometimes there are no other medications to try in this case. They all seem to have one reaction or another.

            So I pushed to get some help to avoid more medical problems with my weight gain and told them I wanted to feel good about myself and enjoy life. It worked, but I went through my family Doctor for the help.

            These steps can teach you what and when to eat and most importantly how much. Its only natural to get the fast food fix even around the house when you always seem hungry, but if you eat the right foods and snacks you never get hungry and sleep better. Most importantly, you burn off what you eat, so you do not gain loads of weight and get depressed.

            Ask for some help and push them to assist you. It works and you will feel much better about yourself and life after you see people really do care.
            PJK

            Comment


            • #7
              weight and appetite

              Teenwithtics
              You asked if anyone has noticed weight or appetite gain on either orap or sertraline.I have a book by H. Winter Griffith,M.D. called the Complete Guide to Prescription and Nonprescription Drugs and it says that sertraline (zoloft) can increase appetite.
              The two worst foods for weight gain are wheat and potatos. Imagine junk food without these two, its almost impossible. We all need some comfort food especially us with ts. When u want some carbs-grains try rice or oats instead. Sounds too exciting? Like anything it depends on how u make it. I used to love oats with carob and pineapple or rice with lots of tamari and flax but I have a bit of a sensitvity to grains and need to stick to a lot of fruits and protein which makes me really thin. Granola or high protein meal replacement bars can be really good too.
              Well best of luck

              Scott

              Comment


              • #8
                Anyone noticed weight gain with Orap?

                Scott,

                When reading about side effects of medications, in this case, increased appetite, look for the incidence of the particular side effect, as reported in the manufacturer's product monograph.

                This is the way your physician would determine whether or not the benefits of the particular medication outweigh the inconvenience of given side effects.

                For example is a particular side effect occurs in 3% of people, then it's not considered troublesome, but if 75% of people, then the therapeutic benefits would really have to be substantial to overcome the occurrence of the side effect.

                Also, some side effects disappear with time, as the body becomes acclimated to the medication.

                Therefore simply stating a particular medication causes a particular side effect, without referring to the frequency it occurs can be misleading.
                Steve

                Dum spiro spero....While I breathe, I hope

                Tourette Canada Homepage
                If you enjoy the TC Forum, please consider a Tourette Canada membership
                Please visit our sister Forum: Psychlinks Psychology and Mental Health Support Forum

                Comment


                • #9
                  percentage of side effects?

                  Steve
                  I agree that you should know the incidence of side effects but if it is already happening to a certain indivdual then it doesnt matter to them if it occurs rarely or not. If a certain med is causing u an unwanted side effect and someone tells u that med can cause that side effect, without knowing or stating the percentage of incidence of that side effect, I dont think its misleading.

                  The only time I remember knowing about med side effects from a prescrip was when there was a sticker on the bottle that said may cause drowsiness. My dr's, I dont recall talking about side effects let alone percentages.

                  The med establishment only have an idea of what the side effects r from a drug based on what researchers claim after testing that drug on a small scale say a few hundred to a few thousand people over a few years at most. This drug is then given to a large pop often tens of thousands to millions. When these patients complain of side effects docs r not required to do anything with this info. They dont report or record it in a database. The government say they want to change this but its the med estab that doesnt want too saying it would take too much time and work. I know one man in the news recently who is also trying to change the way docs report side effects after his daughter died.

                  Pharmaceutacal co's in Canada and around the world have been found guilty in courts of misleading and holding back info on the research they have submitted to Health Canada to get drugs approved. Many times they have been fined for this but fines can be less than profits already made.
                  Drugs r constantly being recalled off the market. Why? cuz the research was incomplete, the side effects where not totally known, we're putting new and relatively unknown chemical compounds in our bodies and people either got seriosly ill or died from the med.

                  Many TSers are on meds and some r havin serious side effects I know that I did and again, I never remember a doc talkin to me about side effects. I have a prescription for medical cannabis which helps me to deal with intense coprolalia and anger with minimal side effects over a long term, over twenty years. Anyways this isnt a promo for med pot it is really just my opinion of presc drugs and the best way to not be mislead is to fully research any drug that has been prescribed to u and to even say to your doc that u would like to try something else if u feel that that med isnt rite for u.

                  I really wish the best to all in their endevors to treat their ts which has proven to be an extremely difficult task for all.

                  Comment


                  • #10
                    Anyone noticed weight gain with Orap?

                    Scott,

                    I won't be the person to defend the pharmaceutical industry; but I will say we cannot indict the entire industry because of the transgressions of a few.

                    As you correctly state, not all physicians discuss medications thoroughly with patients when giving a prescription. I don't believe its because they are trying to hide anything, but more because they are overloaded with work and sometimes take shortcuts.

                    When seeing one's physician, as have suggested elsewhere on the Forum, it helps to be prepared with questions that have been written out beforehand, because it's easy to forget during a visit.

                    If the doctor gives a prescription, be ready with the following questions:

                    How do I take the drug?

                    What can I expect in the way of possible side effects?

                    Are there any interactions with the following medications (both prescribed and over the counter, as well as supplements, herbals etc) that are taken.

                    What should I do if I experience side effects?

                    Those questions should cover the information one needs to know and should reduce the chance for any surprises, plus provide a plan in the event of problems.

                    No medication, whether prescription or over the counter is completely side effect free. The body is an ongoing chemical reaction and a medication alters some part of that chemistry.

                    You are quite right that when a particular adverse reaction happens to you then it represents 100% to you. My point about the frequency of side effects was that one should not discard the idea of taking a medication just because it contains a list of side effects.

                    Your input is appreciated!
                    Steve

                    Dum spiro spero....While I breathe, I hope

                    Tourette Canada Homepage
                    If you enjoy the TC Forum, please consider a Tourette Canada membership
                    Please visit our sister Forum: Psychlinks Psychology and Mental Health Support Forum

                    Comment


                    • #11
                      Anyone noticed weight gain with Orap?

                      In addition to asking the doctor for the details on the medication, don't overlook asking the pharmacist.

                      Many pharmacies now provide a full description of the drug, what it is used for and possible side effects the first time you fill a prescription. Our pharmacist insists on a short consultation when you fill a new prescription to make sure you know how to take the medication, etc. He is also available for consultations when refilling a prescription, or by phone if you have questions about anything to do with the medication.

                      Also, there are a growing number of pharmacists who have training in both "naturopath" and "traditional" medicines and who are able to answer questions on interactions between the two.

                      Choosing a good pharmacist is an important step in your health care.
                      Cathy
                      Forum Moderator

                      Comment


                      • #12
                        Anyone noticed weight gain with Orap?

                        Im going to be totally honest, I havent really read any of the posts in this thread, I just saw the title and wanted to respond. I started taking orap around 7th or 8th grade and that is also the time I jumped from 120 pounds to about 170. I didnt link it to TS or orap, but I wasnt even warned about the possibility of it doing that. I do wonder now if that it was cause by orap or not. But now I think I will read all the posts in this thread and reply back if I have any new info, lol, sorry.
                        The other day at a local grocery store, I saw a rack with books on it and one of them said, "pregancy for dummies"............

                        Comment


                        • #13
                          Anyone noticed weight gain with Orap?

                          Here are some worthwhile online resources to consult in connection with Orap, pimozide:

                          Canadian Product Monograph

                          Drugs.com

                          In their interpretation of the data, Drugs.com states the following under the heading:

                          Other Adverse Effects:

                          Metabolic/Nutritional: Weight gain, weight loss

                          So as you can see the data is not clear, but weight changes appear to have been reported.

                          A possible explanation for weight might can be the sedating effect of this medication, which can lead to decreased physical activity, resulting in less calorie loss...ie weight gain.
                          Steve

                          Dum spiro spero....While I breathe, I hope

                          Tourette Canada Homepage
                          If you enjoy the TC Forum, please consider a Tourette Canada membership
                          Please visit our sister Forum: Psychlinks Psychology and Mental Health Support Forum

                          Comment


                          • #14
                            Anyone noticed weight gain with Orap?

                            i started taking orap when i was 14 and gained quite a bit of weightbut was already a bit overweight

                            what id like to know is what does it do to makeyou gain weight?does it mess with your metabolism?

                            ive taken it for over 10 years but with taking it for that long can your body go back to how it once was?

                            i was up to 260 when i was 18 and should of been like no more then 200, started training like a animal and went down to 175 but was eating a very streict diet as well so i did lose weight but my metabolism was still slow

                            ive been of the orap for like 2mths now and my tics arent that much worse,so ill stay off them,

                            even though it supposlvy supresses your tics it cant be too healthy for you
                            so im glad im off it

                            what amount of orap do you guys and gals take?

                            Comment


                            • #15
                              Anyone noticed weight gain with Orap?

                              I had taken orap and clonidine (spelling?) for about 7 1/2 years (actually, I had taken clonidine for about 13) and I do know my nuerologist would always say to me if I had an issue with a side effect, it more likely would be the orap. She also said if I was to take just one of the two, she has seen better success with orap. I did see improvments when on the drugs, but I think I might have started to become immune to the clonidine and I will be honest, the last year or so of taking them, I wasnt consitant and so my body had a hard time adjusting to them so my side effects seemed worse, but that was more my fault than the drug itself. I have been off both for over a 2 years and I have good times and bad time (currently in a bad tic time, my head twitch is back). I still think every person is different but I do believe some people will most definately benifit from meds and would recommend it. I seem to always hear people talking bad about them.
                              The other day at a local grocery store, I saw a rack with books on it and one of them said, "pregancy for dummies"............

                              Comment

                              Working...
                              X