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Thread: cousin to Clonidine

  1. #1

    Default cousin to Clonidine

    Please excuse my ignorance if this has already been discussed.

    My seven year-old has been on Clonidine for about 3 months now. She has gradually increased her dose until now she takes .05 mg 3x day and .075 mg 1x day. (Gee, I think that dosage is right. I'm not at home right now to check.) She is sleepy during the day and will nap if not occupied with activity. She experiences headaches every couple of days. We have to be careful to keep her blood sugar even or she would have them every day. Her blood pressure is checked every three weeks. She has been referred to a cardiologist because of something that showed up on an ecg done before the start of the drug. (That's all we need...a heart condition too!) She has a repeat ecg next week. Since starting the fourth dose she has also started hallucinating and having very scary dreams. I am praying these side-effects go away soon.

    The doctor is looking into a "cousin" to Clonidine, and I can't remember the drug's name. He said he would consult with the psychiatrist and neurologist first because he needs special permission from the federal government to prescribe this drug due to its high cost. Has anyone heard about this drug and know anything about it?

  2. #2
    Join Date
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    Default cousin to Clonidine

    Hi Redzmum

    This is a link with postings relating to this prescription. Steve has several links amongst the posting to give you more info.

    Click Here for more Info
    Janet, mom of 4

    TSFC Homepage


    "Intelligence is always increasing; accommodation allows your intelligence to do what it has always done." Cassie Green, Washington College

  3. #3
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    Default cousin to Clonidine

    Never hesitate to post a query, even if may have been discussed before. Every discussion is unique and if there happens to be further information on the board, we'll point you to it.

    When you get the opportunity, let us know the name of the compound your physician is considering.

    Do you know if it might be an investigational drug? If the medication happens to be extraordinarily expensive (and what medication isn't??) and it is not covered by your health plan, ask you doctor to call the manufacturer to get some samples.

    Also some pharmaceutical companies have assistance programs for some of their medications when patients on limited means need help with the cost of their drug.

    Once you let us know the name of the drug in question, we can try doing some research.

  4. #4

    Default cousin to Clonidine

    Clonidine is a high-blood pressure medication so I'm guessing that the medication you are thinking of is Tenex (guanaficine)? It's also a high-blood pressure med that is used for reducing ticcing.

  5. #5
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    Default cousin to Clonidine

    It's quite possible that Tenex (Guanfacine) could be the medication in question, though it I don't believe Tenex is approved for use in Canada at this time...which may explain the reason for it's limited uses availability.

    Here's a reference on some work done with Tenex:

    J Am Acad Child Adolesc Psychiatry. 1995 Jan;34(1):50-4.

    An open trial of guanfacine in the treatment of attention-deficit hyperactivity disorder.

    Hunt RD, Arnsten AF, Asbell MD.

    Division of Child Psychiatry, Vanderbilt University School of Medicine, Nashville, TN.

    OBJECTIVE: Medications such as clonidine have been shown to facilitate calming, to enhance frustration tolerance, and to reduce aggression in hyperactive children. The use of guanfacine (Tenex), an alpha 2 noradrenergic agonist similar to clonidine, was studied as an alternative because of its longer excretion half-life, decreased sedative side effects, and more selective binding profile. METHOD: Thirteen psychiatric outpatients diagnosed with ADHD were rated at baseline and while taking guanfacine to determine its efficacy as a treatment for ADHD. Comparisons of Conners parent ratings within subject were used to measure behavioral changes in the subjects. RESULTS: During guanfacine treatment, patients' mean scores improved significantly overall (1.27 off, 0.85 on, t = 2.55, p < .015) and in Conners Hyperactivity (1.63 off, 0.94 on, t = 3.69, p < .01), Inattention (1.92 off, 1.21 on, t = 3.32, p < .01), and Immaturity (1.81 off, 0.92 on, t = 3.77, p < .01) factors. CONCLUSIONS: This preliminary study indicates that guanfacine is a beneficial and useful treatment of ADHD, reducing hyperactive behaviors and enabling greater attentional ability with minimal side effects. We are currently collecting data in a double-blind study measuring guanfacine's efficacy with and in comparison to methylphenidate.

    online pharmacy ref. source: http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract clonidine

  6. #6

    Default cousin to Clonidine

    Yes, I found out today the drug they are considering is TENEX. We are going to wait for now but it will likely be the next one she will have if necessary. Thanks for the great info.

  7. #7
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    Default cousin to Clonidine

    Why is Tenex (guanfacine) being considered for your daughter? What will be the procedure for acquiring the medication?

  8. #8

    Default cousin to Clonidine

    the title of this post interested me as i have been taking clonidine for about 6-7 weeks now
    as i go up in dose the tiredness does come back along with the dry mouth but it subsides after 3-4 days,then i feel fine until i go up again in dose,i am now up to 100 micrograms a day and i have recently started having awful horrific nightmares,so bad that i cant stop thinking about them during the day and it puts me off eating,everytime i try to eat i think about the nightmares,they are really gross.
    i mentioned it to my doc and she said it may be because of the insomnia,our minds do strange things when we lack in sleep.
    so this is interesting that you say your child is also having bad dreams
    could it be related to clonidine?
    jo

  9. #9
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    Default cousin to Clonidine

    Midnight,

    Have a look at This Site that provides an overview of Catapres (clonidine).

    You will notice the listed side effects include increased dream activity, which may be related to the adrenergic or adrenalin activity of the medication.

    Continue reporting any adverse side effects to your physician if the side effects do not subside with time.

  10. #10

    Default cousin to Clonidine

    thanks for the link steve
    it does mention nightmares,i knew about the dry mouth and tiredness but didnt know that it can cause hallucinations and nightmares too :? i have to stay on this until i see a movement specialist next month,i will mention it to him also,
    jo

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